Materials
- TEXT “Organic Chemistry“, D. Klein, 1st or 2nd edition
- Chem 12B Lab Experiments
- Safety goggles or safety glasses
- Calculator
- Alchemie Mechanisms app (iOS and Android), $14.99
- Gradescope to take online Quizzes and Exams – FREE
Recommended Materials
- Molecular Model kit
- ChemAxon chemistry software – MarvinSketch is free (demo version)
- Alchemie ModelAR app
- “Virtual Textbook of Organic Chemistry”
- O=Chem Directory
- Khan Academy
Course Description
This course consists of lecture and lab. Hands-on work and group work will be used to help you learn and understand organic chemistry. Your learning depends on you; you are responsible for your learning. This course is fast-paced and covers a lot of material. Each successive topic builds upon previous topics. To maximize your learning of organic chemistry, focus on the topics covered in lecture, relate these topics to the content in the textbook, try working questions/problems at the end of each chapter, and review frequently. Focus on important points that are covered in lecture and ask questions over material you don’t understand. After each class, review your notes and the assigned chapter and try working more questions/problems. When questions arise, please ask! I am available during office hours or by appointment. In addition, ACCESS Program study sessions and tutoring will be held available for related problem-solving practice.
Chem 12B is a 5 unit course. You are expected to work/study/practice 15 hours per week (9 hours for lecture, 6 hours for lab) in this class.
Course Objectives
- Review CHM 12A substitution, elimination, addition, and acid-base reactions.
- Identify and understand an organic oxidation and reduction reactions.
- Apply substitution and elimination concepts to ethers and epoxides.
- Determine (characterize) the structure of a compound using IR, NMR, MS.
- Identify a conjugated diene and understand electrophilic addition reactions of dienes.
- Identify an aromatic compound and apply substitution, elimination, and oxidation-reduction principles to aromatic side chain reactions.
- Apply addition and elimination concepts to predict electrophilic aromatic substitution reactions (EAS).
- Understand electrophilic aromatic substitution reactions (EAS) of substituted aromatics.
- Understand nucleophilic addition reactions of O and C nucleophiles to C=O compounds
- Understand nucleophilic addition reactions of N nucleophiles to C=O compounds.
- Apply acid-base principles to organic acids.
- Apply nucleophilic addition and elimination concepts to nucleophilic acyl substution reactions of acids and derivatives.
- Apply nucleophilic addition and elimination concepts to enols and enolates reactions.
- Apply acid-base, substitution, and elimination principles to amines.
- Develop synthesis strategies for organic synthesis.
- Apply organic chemistry lab skills, which include the proper use and operation of organic lab chemicals, equipment, instruments, lab tecniques, and safety procedures, to experiments.
Student Learning Outcomes
By the end of the course, you should be able to apply the course objectives to:
(i) Given the name of an organic compound, relate the physical properties, chemical properties, and uses to the compound’s major functional groups and structure.
(ii) Given reactants, predict products and propose mechanisms for organic reactions.
(iii) Given an organic compound, design a synthesis.
(iv) Given IR, NMR, and mass spectrums, deduce the formula and structure of organic compounds.
(v) Demonstrate proficiency in basic laboratory skills used in organic chemistry.